The paper analyzed the effects of spraying selenium fertilizer on the content of cadmium and other heavy metals in rice by pot experiments. The experiments were conducted in the soil that had been polluted by cadmium and other heavy metals in Xiangyin County, with conventional rice varieties Huanghuazhan and Star 2. The results showed that the best treatment of reducing cadmium was 16 g/667 m2 selenium in Huanghuazhan, and 8 g/667 m2 in Xing 2. With the amount of selenium increasing, the effect of reducing cadmium became worse in Xing 2. Application of selenium fertilizer can reduce cadmium in these two rice varieties, but it is difficult to control the amount of cadmium in a permitted range, and the effect is limited.