Excessive amounts of cadmium （Cd） in rice is a big threaten to food safety, which pose a direct health threat to humans. Selenium （Se） is an essential element for human health. Se has an antagonism against Cd and it promotes removing Cd from human body. Based on three years field tests, the author found an effective way to produce fine quality rice （Se-enrich and low Cd rice） in soils of grade II （Soil Quality Standard, total Cd in soil, 0.2~0.6 mg/kg）. These comprehensive measures are described as follows: fertilize Ca-Mg-P after plowing, spread lime during draining and sunning the fields, apply deep water management at mature stage, and fertilize Se foliar-fertilizer at heading stage and milky stage.