Hybrid japonica rice Gengyou 653 was suitable for high-quality rice production in mid-early maturing rice area of Liaoning Province as its excellent eating quality. In the experiment, the effects of hill space and fertilizer amount on yield traits of Gengyou 653 were investigated. The results showed that the amount of nitrogen should be appropriate, the hill space should be longer, the amount of phosphorus should be lower and the amount of potassium should be higher for plant population control and lodging resistance. High-yield could be achieved by increasing the setting ratio, the filled grains per panicle and the 1000-grain weight. The high yield target of Gengyou 653 was 9 750 kg/hm². The suitable hill space was 17.23~18.14 cm, the amount of nitrogen was 109.62~117.48 kg/hm², phosphorus was 30.29~32.74 kg/hm², potassium was 162.94~172.92 kg/hm².