Under the reduction of 18% total chemical fertilizer, the effects of two different controlled-release fertilizers on the growth and yield of rice grew in newly cultivated paddy field were studied. The results showed that application of controlled-release fertilizer could significantly reduce the amount of chemical fertilizer without affecting the yield, and increase the partial productivity of fertilizers. Compared with conventional fertilizer, controlled-release fertilizers increased leaf chlorophyll value in the early stage of rice growth, and increased the number of grains per panicle and grain weight to make up for the lack of effective panicles. In the two controlled-release fertilizers, the effect of organic controlled-release fertilizer was better, its yield, efficiency and partial productivity of fertilizer were increased by 1.1%, 350.4 yuan/hm², and 23.2% compared with conventional fertilizer, respectively. It is suggested that “Holegeng” organic slow-release fertilizer can be popularized and applied as one of the main rice slow-release fertilizer in Yuhang district.