A major challenge faced by high quality rice production is how to increase rice yield without affecting rice quality. This study used 4 common high quality simiao rice varieties and 1 high quality bybrid variety Taifengyou 208 from South China as test materials. In the early and late rice seasons of 2021, an experiment was conducted on the same field in Guangzhou with different nitrogen application rates(N0, 0 kg/hm²; N1, 90 kg/hm²; N2, 135 kg/hm²; N3, 180 kg/hm²). The results showed that the yield of high-quality rice in South China was influenced by five factors, including variety, season, nitrogen application rate, variety×nitrogen application rate interaction effect, and season×variety×nitrogen application rate interaction effect. However, the taste value of rice was only affected by variety and nitrogen application rate. In the early season, there were significant differences in rice yield among varieties under the same nitrogen treatment, but no significant differences in taste value. In the late season, there were significant differences in rice yield among varieties under N1, N2, N3 treatments, while there were significant differences in taste value among varieties under only N3 treatment. The nitrogen application rate is significantly positively correlated with rice yield, with correlation coefficients of 0.977 and 0.950 for the early and late seasons, respectively. The nitrogen application rate is significantly negative correlated with taste value, with correlation coefficients of -0.972 and -0.956 for the early and late seasons, respectively. Based on the experimental results, a suitable nitrogen application rate was proposed to maintain high yield and excellent taste of high-quality rice in South China.