Zizhong County is a representative area for rice production in the hilly regions of Sichuan Province. Through years of technological integration and innovation, it has achieved a significant increase in rice yield per unit area. This paper systematically reviews the high-quality and high-yield rice cultivation technology system in Zizhong County, with a focus on key aspects such as variety selection, dry nursery seedling technology, “Dasanwei” intensive cultivation, scientific fertilization and irrigation, integrated pest management, and the “Five-Excellent Factors” integration model. It further examines the challenges faced in the process of technological integration and innovation, including high initial costs hindering large-scale adoption, uneven application and implementation rates of technologies, ecological risks arising from long-term monoculture, resource constraints and insufficient exploitation of potential. On this basis, the study proposes development strategies such as promoting the simplification and smart upgrading of technologies, advancing ecological and green low-carbon transformation, enhancing industrial integration and value chain development, and innovating management systems and service mechanisms. The technological practices in Zizhong County offer a replicable pathway for high-yield and high-quality rice cultivation in the hilly areas of Southern China, holding practical significance for ensuring regional food security.