As one of the main food crops in china, the production safety of rice is seriously threatened by the cadmium contamination in paddy fields. The development of agronomic practice which is economic and efficient for the regulation of cadmium contamination in rice has drawn wide attention. This paper briefly expounded a serious of researches and applications in agronomic practices for the regulation of cadmium contamination in rice, such as water management, rational fertilization technique, foliar fertilizer application, in-situ passivation technique, microbiological remediation, adjustment of cropping system, planting of cultivars with low accumulation of cadmium and so on, also discussed the disadvantages of these agronomic practices and proposed the direction of future development. It is expected to provide academic reference and technical support for more effective regulation of cadmium contamination in rice.